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Non-small cell lung cancer (NSCLC)

Current concepts of radiation therapy

Radiation therapy forms an integral component in the management of NSCLC. Recent advances in radiation therapy in NSCLC are based on both technical advances and the better understanding of the radiation biology of tolerances of normal tissues and the highest tolerable maximum tumor doses. ­Stereotactic body radiotherapy is now an acceptable treatment option for early stage peripherally situated NSCLC in ­patients unfit to undergo definitive surgery. Other recent strate­gies involve radiation dose escalation, use of PET-CT based treatment planning, isotoxic radiation therapy and use of particle beam radiotherapy.